N-Terminal modification

Acetylation
Formylation
Biotin
Palm, Myr,Lauryl
TFA
Bzo
Abz
Maleimide
Chloroacetylation, bromoacetylation
Suc
Hynic
DOTA、NOTA (Chelating Peptides)
C-Terminal modification
Amidation
Esterification
AMC
AFC
PNA

D-form amino acids

D-Ala、D-Arg、D-Asn、D-Asp、D-Cys、D-Gln、D-Glu、D-His、D-Ile、D-Lys、D-Leu、D-Met、D-Phe、D-Pro、D-Ser、D-Thr、D-Trp、D-Tyr、D-Ser
D-Abu、D-Bal、D-Cha、D-Cit、D-Hyp、D-Nle、D-Nal、D-Nva、D-Orn、D-Tic、D-Pen

N-methylated modification：

NMe-His、NMe-Met、NMe-Gly、NMe-Ala、NMe-Asn、NMe-Asp、NMe-Arg、NMe-Cys、NMe-Glu、NMe-Gln、NMe-Leu、NMe-Ile、NMe-Lys、NMe-Ser、NMe-Thr、NMe-Trp、NMe-Val、NMe-Nle、NMe-Phe Lys(Me)、Lys(Me)2、Lys(Me)3、Arg(Me)、Arg(Me)2S、Arg(Me)2AS、Cys(Me)、Asp(OMe)、Glu(OMe)、Tyr(Me)、Trp(Me)

Fluorescent modification

FAM、FITC、TAMRA、Bodipy、Cy5、Cy7
DansylChlorde、Mca、Dabcyl、Dnp、CarboxyRhodamine110、7OHCCA、Tide Fluor
、Alexa Fluor 、Texas Red、QSY、Atto
DACIA、Farnesyl
Edans
Dabcyl+Edans
Mca+Dnp
FITC+5FAM
5FAM+TQ2Cy5+QSY21
6FAM+QSY9
5TAMRA+QSY7
DNP+DACIA5FAM+Farnesyl
Tide Fluor 555+Tide Fluor 647
Tide Fluor 488+Tide Flour550

Phosphorylation marker

p-Tyr
p-Ser
p-Thr

Isotope labelling

D and L form amino acids , 13C，15N，D and 18O

Other side chain modifications

Tyr(3-Cl)、Tyr(3-NO2)、Tyr(SO3H2)
Phe(4-Cl)、Phe(4-NO2)、Phe(3-Cl）、Phe(4-CF3)
Ser(Butanoyl)、Ser(Octanoyl)、Ser(Palm)、Ser(Laury)、Ser(Myr)

PEG modifications

PEG2、PEG4、PEG8、PEG12、PEG2000、PEG5000

Cyclo peptides

stapled and stiched peptide
Mono Disulfide bridge
Double Disulfide bridge
Triple Disulfide bridge
Random Triple Disulfide bridge
Amide cyclic (end)
Amide cyclic (Side chain)

Protein coupling

KLH (Keyhole Limpet Hemocyanin)
BSA (Bovine Serum Albumin)
OVA (Ovalbumin)

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